New 3-<i>O</i>-substituted xanthone derivatives as promising acetylcholinesterase inhibitors
Zi Han Loh, Huey Chong Kwong, Kok Wai Lam, Soek Sin Teh, Gwendoline Cheng Lian Ee, Ching Kheng Quah, Anthony Siong Hock Ho, Siau Hui Mah
Abstract
which can be further developed into potent AChE inhibitors.
Topics & Concepts
ChemistryXanthoneAcetylcholinesteraseButyrylcholinesteraseStereochemistryAchéDocking (animal)Alkoxy groupIndole testHydrogen bondEnzymeBiochemistryOrganic chemistryMoleculeNursingMedicineAlkylCholinesterase and Neurodegenerative DiseasesChemical synthesis and alkaloidsFree Radicals and Antioxidants