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Simultaneous single-cell analysis of 5mC and 5hmC with SIMPLE-seq

Dongsheng Bai, Xiaoting Zhang, Huifen Xiang, Zijian Guo, Chenxu Zhu, Chengqi Yi

2024Nature Biotechnology46 citationsDOI

Topics & Concepts

5-HydroxymethylcytosineEpigenomeDNA methylationEpigeneticsComputational biologyBiologySingle-cell analysis5-MethylcytosineDNACellCell biologyGeneGeneticsGene expressionEpigenetics and DNA MethylationSingle-cell and spatial transcriptomicsRNA modifications and cancer
Simultaneous single-cell analysis of 5mC and 5hmC with SIMPLE-seq | Litcius