Doxorubicin induced cardio toxicity through sirtuins mediated mitochondrial disruption
Nisar Ahmad, Arfan Ullah, Peng Chu, Wenzhang Tian, Zeyao Tang, Zhaolin Sun
Topics & Concepts
CardiotoxicitySIRT3PharmacologySirtuinMitochondrionOxidative stressMitochondrial permeability transition poreMitochondrial ROSDoxorubicinChemistryBiologyCell biologyProgrammed cell deathMedicineBiochemistryToxicityInternal medicineApoptosisNAD+ kinaseEnzymeChemotherapyChemotherapy-induced cardiotoxicity and mitigationSirtuins and Resveratrol in MedicineCalcium signaling and nucleotide metabolism