Evolving the 3-O/6-O regiospecificity of a microbial glycosyltransferase for efficient production of ginsenoside Rh1 and unnatural ginsenoside
Jianlin Chu, Lu Zhao, Xiaoli Xu, Yuting Li, Bin Wu, Song Qin, Bingfang He
Topics & Concepts
RegioselectivityGinsenosideChemistryGlycosyltransferaseMutantGlycosylationEnzymeProtein engineeringDirected evolutionYield (engineering)StereochemistryBiochemistryCatalysisGinsengGeneMaterials scienceMedicinePathologyAlternative medicineMetallurgyGinseng Biological Effects and ApplicationsPlant tissue culture and regenerationPharmacological Effects of Natural Compounds