Photocatalyst-free light-mediated three-component alkoxy-, hydroxy-, and azidotrifluoromethylation of alkenes
Yingmin Ji, Aida Jaafar, Carolina Gimbert‐Suriñach, M. Ribagorda, Adelina Vallribera, Albert Granados, María Jesús Cabrera‐Afonso
Abstract
A photocatalyst-free method enables efficient alkene difunctionalization in CF 3 -rich organic environments using accessible starting materials. This protocol is applicable for the synthesis of alkoxy, hydroxy, and azido derivatives.
Topics & Concepts
ChemistryAlkoxy groupComponent (thermodynamics)PhotocatalysisPhotochemistryOrganic chemistryCatalysisAlkylThermodynamicsPhysicsFluorine in Organic ChemistryRadical Photochemical Reactions