Synthesis of polymeric micelles with dual-functional sheddable PEG stealth for enhanced tumor-targeted drug delivery
Lu Sun, Hua Wei, Xianshuo Zhang, Chao Meng, Guiying Kang, Wei Ma, Liwei Ma, Baoyan Wang, Cui‐Yun Yu
Abstract
We reported the synthesis of polymeric micelles with a dual-functional sheddable mPEG stealth to realize simultaneously tumor-triggered targeting and intracellular micelle destabilization for enhanced anticancer drug delivery.
Topics & Concepts
MicelleDrug deliveryPEG ratioDrugChemistryDual (grammatical number)IntracellularTargeted drug deliveryDrug carrierNanotechnologyCombinatorial chemistryBiophysicsPharmacologyMaterials scienceMedicineBiochemistryOrganic chemistryBiologyBusinessAqueous solutionArtFinanceLiteratureNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsRNA Interference and Gene Delivery