BCL2L1 inhibitor A-1331852 inhibits MCL1 transcription and triggers apoptosis in acute myeloid leukemia cells
Jing‐Ting Chiou, Yuying Wu, Yuan‐Chin Lee, Long‐Sen Chang
Topics & Concepts
MCL1CREBU937 cellDownregulation and upregulationp38 mitogen-activated protein kinasesCell biologyTranscription factorApoptosisProgrammed cell deathCancer researchChemistryPhosphorylationEctopic expressionMAPK/ERK pathwayBiologyBiochemistryGeneCell death mechanisms and regulationUbiquitin and proteasome pathwaysAutophagy in Disease and Therapy