Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking
Zhe Zhang, Meirong Bai, Guilherme Oliveira Barbosa, Andrew Chen, Yuehua Wei, Shuo Luo, Xin Wang, Bingying Wang, Tatsuya Tsukui, Hao Li, Dean Sheppard, Thomas B. Kornberg, K. Dengke
Abstract
Collagen production and secretion in cells of diverse organisms require a novel family of transmembrane proteins.
Topics & Concepts
IntracellularCell biologyIntracellular transportSecretory proteinChemistryBiologyComputational biologyBiochemistrySecretionCerebrovascular and genetic disordersBone and Dental Protein StudiesTissue Engineering and Regenerative Medicine