Genetic modifiers of Huntington disease differentially influence motor and cognitive domains
Jong‐Min Lee, Yuan Huang, Michael Orth, Tammy Gillis, Jacqueline Siciliano, Eunpyo Hong, Jayalakshmi Srinidhi Mysore, Diane Lucente, Vanessa C. Wheeler, Ihn Sik Seong, Zachariah L. McLean, James A. Mills, Branduff McAllister, S. V. Lobanov, Thomas H. Massey, Marc Ciosi, G. Bernhard Landwehrmeyer, Jane S. Paulsen, E. Ray Dorsey, Ira Shoulson, Cristina Sampaio, Darren G. Monckton, Seung Kwak, Peter Holmans, Lesley Jones, Marcy E. MacDonald, Jeffrey D. Long, James F. Gusella
Topics & Concepts
BiologyGeneticsHuntington's diseaseDiseasePhenotypeGenome-wide association studyImputation (statistics)PMS2Locus (genetics)Genetic associationNeuroscienceComputational biologyGeneSingle-nucleotide polymorphismDNA repairGenotypeMedicineDNA mismatch repairMissing dataMachine learningPathologyComputer scienceGenetic Neurodegenerative DiseasesMitochondrial Function and PathologyFungal and yeast genetics research