Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation
Craig Donoghue, Monica Cubillos‐Rojas, Nuria Martí Gutiérrez, Carolina Sánchez, Xavier Verdaguer, Antoni Riéra, Ángel R. Nebreda
Topics & Concepts
ChemistryLinkerDegradation (telecommunications)Small moleculeMoleculeCombinatorial chemistryStereochemistryBiophysicsBiochemistryOrganic chemistryTelecommunicationsComputer scienceBiologyOperating systemProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis