Nitrofuran drugs beyond redox cycling: Evidence of Nitroreduction-independent cytotoxicity mechanism
Carlos Gallardo‐Garrido, Younghoon Cho, Javiera Cortés‐Ríos, David Vásquez, C. David Pessoa‐Mahana, Ramiro Araya‐Maturana, H. Pessoa‐Mahana, Mario Faúndez
Topics & Concepts
NitrofuranChemistryGlutathioneCytotoxicityBiochemistryAntioxidantReactive oxygen speciesToxicityPharmacologyEnzymeIn vitroBiologyOrganic chemistryGeneticsSynthesis and Catalytic ReactionsChemical Reaction MechanismsPhenothiazines and Benzothiazines Synthesis and Activities