Pyrethrum extract induces oxidative DNA damage and AMPK/mTOR-mediated autophagy in SH-SY5Y cells
Yun Yang, Yang Zhang, Jufang Gao, Wenping Xu, Zhiping Xu, Zhong Li, Jiagao Cheng, Liming Tao
Topics & Concepts
AMPKPyrethrumAutophagyPI3K/AKT/mTOR pathwayProtein kinase ADNA damageChemistryCytotoxicityViability assayCytotoxic T cellPharmacologyCell biologyBiologyPhosphorylationIn vitroBiochemistrySignal transductionDNAApoptosisPesticideAgronomyAutophagy in Disease and TherapyToxin Mechanisms and ImmunotoxinsGenomics, phytochemicals, and oxidative stress