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Short- and long-term exposures of the synthetic cannabinoid 5F-APINAC induce metabolomic alterations associated with neurotransmitter systems and embryotoxicity confirmed by teratogenicity in zebrafish

Pavel A. Markin, Alex Brito, Natalia E. Moskaleva, Franco Tagliaro, Michael R. La Frano, Mark V. Savitskii, Svetlana A. Appolonova

2021Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology23 citationsDOI

Topics & Concepts

CannabinoidSynthetic cannabinoidsChronic toxicityPharmacologyNeurotransmitterNeurotransmissionChemistryKynurenineAcute exposureInternal medicineAcute toxicityToxicityEndocrinologyMedicineTryptophanCentral nervous systemBiochemistryAmino acidReceptorZebrafish Biomedical Research ApplicationsCannabis and Cannabinoid ResearchNeurotransmitter Receptor Influence on Behavior
Short- and long-term exposures of the synthetic cannabinoid 5F-APINAC induce metabolomic alterations associated with neurotransmitter systems and embryotoxicity confirmed by teratogenicity in zebrafish | Litcius