Body composition measured by computed tomography is associated with colorectal cancer survival, also in early-stage disease
Mona Shirdel, Fredrick Andersson, Robin Myte, Jan Axelsson, Martin Rutegård, Lennart Blomqvist, Katrine Riklund, Bethany Van Guelpen, Richard Palmqvist, Björn Gylling
Abstract
In concordance with previous studies, sarcopenia and myosteatosis were associated with decreased cancer-specific survival. The strong association between sarcopenia and poor cancer-specific survival in early-stage disease could have clinical implications for personalizing therapy decisions, including nutritional support.
Topics & Concepts
MedicineSarcopeniaHazard ratioColorectal cancerProportional hazards modelCachexiaInternal medicinePopulationCancerAdipose tissueRetrospective cohort studyConfidence intervalSurvival analysisSurvival rateOncologyEnvironmental healthNutrition and Health in AgingFrailty in Older AdultsBody Composition Measurement Techniques