In Situ Fucosylation of the Wnt Co-receptor LRP6 Increases Its Endocytosis and Reduces Wnt/β-Catenin Signaling
Senlian Hong, Lei Feng, Yi Yang, Hao Jiang, Xiaomeng Hou, Peng Guo, Florence L. Marlow, Pamela Stanley, Peng Wu
Topics & Concepts
Wnt signaling pathwayEndocytosisLRP6ChemistryCell biologyIn situFucosylationReceptorSignal transductionBiologyBiochemistryGlycoproteinOrganic chemistryGlycanWnt/β-catenin signaling in development and cancerGalectins and Cancer BiologyGlycosylation and Glycoproteins Research