Protein-structure-dependent spectral shifts of near-infrared photoluminescence from locally functionalized single-walled carbon nanotubes based on avidin–biotin interactions
Yoshiaki Niidome, Rie Wakabayashi, Masahiro Goto, Tsuyohiko Fujigaya, Tomohiro Shiraki
Abstract
* PL shift behaviors of the lf-SWCNTs-b change noticeably when avidin and streptavidin are introduced compared to the case with neutravidin. This is due to the different microenvironments formed at the biotin-doped sites, attributed to the difference in the structural features of the introduced avidin derivatives. Moreover, we successfully enhance the detection signals of lf-SWCNTs-b (>three fold) for streptavidin detection using a fabricated film device. Therefore, lf-SWCNTs exhibit significant promise for application in advanced protein detection/recognition devices based on NIR PL.
Topics & Concepts
AvidinCarbon nanotubeStreptavidinPhotoluminescenceBiotinMaterials scienceAdsorptionDopingSurface modificationNanotechnologyBlueshiftChemical engineeringPhotochemistryChemistryOptoelectronicsOrganic chemistryPhysical chemistryEngineeringBiochemistryCarbon Nanotubes in CompositesMechanical and Optical ResonatorsNeuroscience and Neural Engineering