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How metabolism bridles cytotoxic CD8+ T cells through epigenetic modifications

Heleen H. Van Acker, Shixin Ma, Tommaso Scolaro, Susan M. Kaech, Massimiliano Mazzone

2021Trends in Immunology35 citationsDOIOpen Access PDF

Topics & Concepts

Cytotoxic T cellEpigeneticsBiologyTumor microenvironmentCD8T-cell receptorImmunologyAdoptive cell transferChimeric antigen receptorCell biologyT cellCancer researchAntigenImmune systemBiochemistryGeneIn vitroCAR-T cell therapy researchImmune Cell Function and InteractionHistone Deacetylase Inhibitors Research
How metabolism bridles cytotoxic CD8+ T cells through epigenetic modifications | Litcius