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Discovery of indoline-based derivatives as effective ROCK2 inhibitors for the potential new treatment of idiopathic pulmonary fibrosis

Suhong Fu, Yi Wen, Bin Peng, Minghai Tang, Mingsong Shi, Jiang Liu, Yingxue Yang, Wenting Si, Yong Guo, Xiandeng Li, Tingting Yan, Jie Kang, Heying Pei, Lijuan Chen

2023Bioorganic Chemistry16 citationsDOI

Topics & Concepts

IndolineChemistryPulmonary fibrosisIdiopathic pulmonary fibrosisPharmacologyFibrosisLungInternal medicineStereochemistryMedicineInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisPeptidase Inhibition and AnalysisLung Cancer Treatments and Mutations
Discovery of indoline-based derivatives as effective ROCK2 inhibitors for the potential new treatment of idiopathic pulmonary fibrosis | Litcius