Loss of the proprotein convertase Furin in T cells represses mammary tumorigenesis in oncogene-driven triple negative breast cancer
Zongsheng He, Abdel‐Majid Khatib, John W.M. Creemers
Topics & Concepts
FurinProprotein convertaseCancer researchTumor initiationImmune systemOncogeneCarcinogenesisTriple-negative breast cancerCancerMetastasisTumor progressionBiologyDownregulation and upregulationCD8ImmunologyBreast cancerMedicineInternal medicineEndocrinologyCell cycleLDL receptorCholesterolBiochemistryGeneLipoproteinEnzymeCancer Immunotherapy and BiomarkersUbiquitin and proteasome pathwaysImmune cells in cancer