Triazole-estradiol analogs: A potential cancer therapeutic targeting ovarian and colorectal cancer
Trevor Ostlund, Faez Alotaibi, Jennifer Kyeremateng, Hossam Halaweish, Abigail Kasten, Surtaj H. Iram, Fathi T. Halaweish
Topics & Concepts
PharmacophoreOvarian cancerCancer researchColorectal cancerMAPK/ERK pathwayCell cultureEpidermal growth factor receptorPharmacologyChemistryEGFR inhibitorsCancerCell growthMechanism of actionPI3K/AKT/mTOR pathwayKinaseBiologySignal transductionIn vitroBiochemistryReceptorMedicineInternal medicineGeneticsChronic Myeloid Leukemia TreatmentsChronic Lymphocytic Leukemia ResearchCancer therapeutics and mechanisms