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Replacement per- and polyfluoroalkyl substances (PFAS) are potent modulators of lipogenic and drug metabolizing gene expression signatures in primary human hepatocytes

Emily Marques, Marisa Pfohl, Wei Wei, Giuseppe Tarantola, Lucie C. Ford, Ogochukwu Amaeze, Jessica Alesio, Sangwoo Ryu, Xuelian Jia, Hao Zhu, Geoffrey D. Bothun, Angela L. Slitt

2022Toxicology and Applied Pharmacology52 citationsDOIOpen Access PDF

Topics & Concepts

Primary (astronomy)DrugGeneChemistryPharmacologyGene expressionCancer researchBiologyBiochemistryAstronomyPhysicsPer- and polyfluoroalkyl substances researchToxic Organic Pollutants ImpactEffects and risks of endocrine disrupting chemicals
Replacement per- and polyfluoroalkyl substances (PFAS) are potent modulators of lipogenic and drug metabolizing gene expression signatures in primary human hepatocytes | Litcius