Structure and thiazide inhibition mechanism of the human Na–Cl cotransporter
Minrui Fan, Jianxiu Zhang, Chien-Ling Lee, Jinru Zhang, Liang Feng
Topics & Concepts
ThiazideDistal convoluted tubuleCotransporterReabsorptionSymporterMechanism (biology)ChemistryEndocrinologyInternal medicinePharmacologyProximal tubuleDiureticSodiumMedicineTransporterKidneyBiochemistryGenePhilosophyEpistemologyOrganic chemistryIon Transport and Channel RegulationSodium Intake and HealthMagnesium in Health and Disease