Chemo- and regioselective nucleophilic hydrofunctionalization of unactivated aliphatic alkenes under transition-metal-free catalysts
Ying Zhan, Yao Zhao, Qiang Du, Jiacheng Rui, Rizhi Chen, Xintao Zheng, Xiaojin Wu
Abstract
A transition-metal-free-catalyzed nucleophilic hydrofunctionalization of both terminal and internal unactivated aliphatic alkenes has been developed for the construction of structurally complex β-substituted aliphatic amides.
Topics & Concepts
RegioselectivityCatalysisNucleophileTransition metalChemistryNucleophilic additionOrganic chemistryMetalAlkenePolymer chemistryCatalytic C–H Functionalization MethodsChemical Synthesis and AnalysisAsymmetric Hydrogenation and Catalysis