Screening and optimization of shark nanobodies against SARS-CoV-2 spike RBD
Xiaochun Liu, Yanqing Wang, Li-shan Sun, Guokai Xiao, Ning Hou, Jin Chen, Wei Wang, Ximing Xu, Yuchao Gu
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Recombinant DNANeutralizationNeutralizing antibodyAntibodySpike ProteinVirologyPhage displayCoronavirus disease 2019 (COVID-19)BiologyPeptide libraryCoronavirus2019-20 coronavirus outbreakComputational biologyGeneGeneticsPeptide sequenceMedicineInfectious disease (medical specialty)PathologyOutbreakDiseaseSARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies ResearchBacteriophages and microbial interactions