Tandem Ubiquitin Binding Entities (TUBEs) as Tools to Explore Ubiquitin-Proteasome System and PROTAC Drug Discovery
Karteek Kadimisetty, Katie J. Sheets, Patrick H. Gross, Myra J. Zerr, Dahmane Ouazia
Topics & Concepts
UbiquitinProteasomeDrug discoveryComputational biologyCell biologyBiologyDrug developmentDeubiquitinating enzymeBiochemistryTarget proteinChemistryDrugGenePharmacologyUbiquitin and proteasome pathwaysProtein Degradation and InhibitorsPeptidase Inhibition and Analysis