Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age
Niamh McGarry, Carol Murray, Sean Garvey, Abigail Wilkinson, Lucas Silva Tortorelli, Lucy Ryan, Lorna Hayden, Dáire Healy, Éadaoin W. Griffin, Edel Hennessy, Malathy Arumugam, Donal Skelly, Kevin J. Mitchell, Colm Cunningham
Topics & Concepts
Innate immune systemIRF7ImmunologyImmune systemInflammationRNA silencingSickness behaviorBiologyDiseaseRNAMedicineRNA interferenceGeneInternal medicineGeneticsRNA regulation and diseaseImmune Response and InflammationInflammasome and immune disorders