Recognition of G-quadruplex topology through hybrid binding with implications in cancer theranostics
Yelisetty Venkata Suseela, Pardhasaradhi Satha, N. Arul Murugan, Thimmaiah Govindaraju
Abstract
therapeutic efficacy supplemented with tumor 3D spheroid and tissue imaging potential define the role of TGP18 in GQ-targeted cancer theranostics.
Topics & Concepts
G-quadruplexCancerCancer researchTopology (electrical circuits)Computational biologyComputer scienceNanotechnologyMedicineBiologyMaterials scienceMathematicsInternal medicineDNAGeneticsCombinatoricsDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery