Litcius/Paper detail

How collagen becomes ‘stiff’

Rebecca G. Wells

2022eLife21 citationsDOIOpen Access PDF

Abstract

Oxidative stress following a lung injury can alter the structure of collagen, causing it to stiffen and trigger the formation of a fibrotic scar that further hardens the tissue.

Topics & Concepts

ChemistryCell biologyBiologyTissue Engineering and Regenerative MedicineElectrospun Nanofibers in Biomedical ApplicationsMesenchymal stem cell research