Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment
Khiem C. Lam, Romina E. Araya, April Huang, Quanyi Chen, Martina Di Modica, Richard R. Rodrigues, Amélie Lopès, Sarah B. Johnson, Benjamin Schwarz, Eric Bohrnsen, Alexandria P. Cogdill, Catharine M. Bosio, Jennifer A. Wargo, Maxwell P. Lee, Romina S. Goldszmid
Topics & Concepts
BiologyTumor microenvironmentImmune systemInnate immune systemReprogrammingImmunologyMacrophage polarizationCancer researchInterferonImmunotherapyCrosstalkCancer immunotherapyMacrophageCellPhysicsOpticsGeneticsBiochemistryIn vitroImmune cells in cancerCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction