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Catalytic enantioselective oxysulfenylation of <i>o</i>-vinylanilides

Arunachalam Kesavan, Pazhamalai Anbarasan

2021Chemical Communications23 citationsDOI

Abstract

-(aryl/alkylthio)imides. The developed reaction offers access to diverse substituted aryl/alkylthio tethered 3,1-benzoxazines in excellent yields and enantiomeric ratios. Furthermore, synthetic applications of benzoxazines and aryl/alkylthio moieties and a transition state model for the observed enantioselectivity are also discussed.

Topics & Concepts

Enantioselective synthesisArylCatalysisEnantiomerChemistryReaction conditionsCombinatorial chemistryStereochemistryOrganic chemistryAlkylSulfur-Based Synthesis TechniquesSynthesis and Catalytic ReactionsChemical Synthesis and Reactions
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