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Anti-4-1BB immunotherapy enhances systemic immune effects of radiotherapy to induce B and T cell-dependent anti-tumor immune activation and improve tumor control at unirradiated sites

Alexandra Martin, Chase Powell, Mate Z Nagy, Patrick Innamarato, John J. Powers, Derek A. Nichols, Carmen M. Anadon, Ricardo A. Chaurio, Sungjune Kim, Min-Hsuan Wang, Bing Gong, Xianzhe Wang, Thomas J. Scheutz, Scott Antonia, José R. Conejo-García, Bradford A. Perez

2022Cancer Immunology Immunotherapy15 citationsDOIOpen Access PDF

Topics & Concepts

Immune systemImmunotherapyTumor microenvironmentCancer researchT cellMedicineCD8Cytotoxic T cellImmunologyTumor antigenAntigen presentationBiologyIn vitroBiochemistryCancer Immunotherapy and BiomarkersImmunotherapy and Immune ResponsesCAR-T cell therapy research
Anti-4-1BB immunotherapy enhances systemic immune effects of radiotherapy to induce B and T cell-dependent anti-tumor immune activation and improve tumor control at unirradiated sites | Litcius