PCR-based profiling of transcription factor activity in vivo by a virus-based reporter battery
Hitomi Abe, Kentaro Abe
Abstract
The TFAP obtained by our method will help bridge the information gap between the genome and transcriptome and aid the multi-omics view of understanding the gene regulation system.
Topics & Concepts
TranscriptomeComputational biologyReporter geneBiologyTranscription factorIn vivoPopulationGeneGene expressionGene expression profilingCell biologyGeneticsMedicineEnvironmental healthCRISPR and Genetic EngineeringVirus-based gene therapy researchRNA and protein synthesis mechanisms