Development of an amine transaminase-lipase cascade for chiral amide synthesis under flow conditions
Antía Pintor, Ashley P. Mattey, Iván Lavandera, Vicente Gotor‐Fernández, Alexey Volkov
Abstract
An amine transaminase and a lipase have been immobilised in separated reactors containing EziG polymer-coated controlled porosity glass carrier materials to transform 1-phenoxypropan-2-one into the corresponding ( R )-acetamide in organic solvent.
Topics & Concepts
AcetamideLipaseAmine gas treatingAmideChemistrySolventTransaminaseOrganic chemistryPolyamideEnzymeInnovative Microfluidic and Catalytic Techniques InnovationAnalytical Chemistry and ChromatographyEnzyme Catalysis and Immobilization