An integrative metabolomics and network pharmacology method for exploring the effect and mechanism of Radix Bupleuri and Radix Paeoniae Alba on anti-depression
Hongcai Zhang, Shuxiang Zhang, Mingxu Hu, Yanyan Chen, Wenran Wang, Ke Zhang, Haixue Kuang, Qiuhong Wang
Topics & Concepts
Radix (gastropod)AntidepressantPharmacologyTraditional Chinese medicineMetabolomicsKEGGDrugMetabolic pathwayMechanism (biology)ChemistryDrug metabolismTraditional medicineMetabolismBiochemistryMedicineBiologyGene expressionGeneAnxietyTranscriptomePsychiatryEpistemologyPhilosophyAlternative medicineBotanyPathologyChromatographyTryptophan and brain disordersMetabolomics and Mass Spectrometry StudiesComputational Drug Discovery Methods