Synthesis, acetylcholinesterase and butyrylcholinesterase inhibitory potential and molecular docking study of thiazole bearing thiourea analogues
Hayat Ullah, Mehvish Jabeen, Fazal Rahim, Amjad Hussain, Fahad Khan, Muhammad Perviaz, Muhammad Sajid, Imad Uddin, Muhammad Usman Khan, Muhammad Nabi
Topics & Concepts
ButyrylcholinesteraseAcetylcholinesteraseThioureaThiazoleChemistryStereochemistryAchéDocking (animal)IC50Inhibitory postsynaptic potentialSubstituentEnzymeBiochemistryIn vitroOrganic chemistryBiologyNeuroscienceNursingMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsSynthesis and biological activity