Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel
Haitao Wang, Sen Guo, Seung-Jin Kim, Fangyuan Shao, Joshua W. K. Ho, Kuan Un Wong, Zhengqiang Miao, Dapeng Hao, Ming Zhao, Jun Xu, Jianming Zeng, Koon Ho Wong, Lijun Di, Ada Hang‐Heng Wong, Xiaoling Xu, Chu‐Xia Deng
Abstract
Thus, cisplatin prevents breast cancer metastasis through blocking early EMT, and the combination of cisplatin and paclitaxel represents a promising therapy for killing breast cancer and blocking tumor metastasis.
Topics & Concepts
CisplatinMetastasisCancer researchPaclitaxelCancer cellCancerBreast cancerEpithelial–mesenchymal transitionBiologyMedicineOncologyInternal medicineChemotherapyCancer Cells and MetastasisKruppel-like factors researchCancer-related Molecular Pathways