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Clinical Trials Affected by Research Grant Terminations at the National Institutes of Health

Vishal R. Patel, Michael Liu, Anupam B. Jena

2025JAMA Internal Medicine14 citationsDOIOpen Access PDF

Abstract

This cross-sectional study summarizes the number of trials with terminated grants from the National Institutes of Health (NIH) and calculates the proportion of affected trials among those with previously active NIH funding, by trial status at time of grant termination and by trial characteristics.

Topics & Concepts

MedicineClinical trialFamily medicineMEDLINEAlternative medicinePublic healthGerontologyGrant fundingClinical researchHealth services researchResearch designTrial registrationHealth and Medical Research ImpactsMeta-analysis and systematic reviewsStatistical Methods in Clinical Trials
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