Ni-Catalyzed direct iminoalkynylation of unactivated olefins with terminal alkynes: facile access to alkyne-labelled pyrrolines
Xingjie Zhang, Di Qi, Chenchen Jiao, Zhiguo Zhang, Xiaopan Liu, Guisheng Zhang
Abstract
The first example of iminoalkynylation of unactivated olefins with terminal alkynes was achieved by a nickel-catalyzed iminyl-radical cyclization/Sonogashira-type coupling sequence.
Topics & Concepts
AlkyneChemistrySonogashira couplingCatalysisTerminal (telecommunication)Combinatorial chemistryMedicinal chemistryOrganic chemistryPalladiumTelecommunicationsComputer scienceCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques