Characterization of Powder- and Tablet Properties of Different Direct Compaction Grades of Mannitol Using a Kohonen Self-organizing Map and a Lasso Regression Model
Atsushi Kosugi, Kok Hoong Leong, Hinako Tsuji, Yoshihiro Hayashi, Shungo Kumada, Kotaro Okada, Yoshinori Onuki
Topics & Concepts
CompactionMannitolMaterials scienceParticle sizeUltimate tensile strengthLinear regressionFriabilityDosage formComposite materialChromatographyMathematicsChemistryChemical engineeringStatisticsPolymerEngineeringOrganic chemistryEthyl celluloseDrug Solubulity and Delivery SystemsProtein purification and stabilitySpectroscopy and Chemometric Analyses