The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element
Agnieszka Markowska, Adam R. Markowski, Iwona Jarocka-Karpowicz
Abstract
6-aminohexanoic acid is an ω-amino acid with a hydrophobic, flexible structure. Although the ω-amino acid in question is mainly used clinically as an antifibrinolytic drug, other applications are also interesting and important. This synthetic lysine derivative, without an α-amino group, plays a significant role in chemical synthesis of modified peptides and in the polyamide synthetic fibers (nylon) industry. It is also often used as a linker in various biologically active structures. This review concentrates on the role of 6-aminohexanoic acid in the structure of various molecules.
Topics & Concepts
PolyamideChemistryLinkerLysineAmino acidDerivative (finance)Combinatorial chemistryPolymer chemistryBiochemistryComputer scienceOperating systemEconomicsFinancial economicsBiopolymer Synthesis and ApplicationsChemical Synthesis and AnalysisProtein purification and stability