A three-dimensional multipedal DNA walker for the ultrasensitive detection of tumor exosomes
Huizhen Wang, Kejing Wan, Yue Zhou, Xiaoxiao He, Dinggeng He, Hong Cheng, Jin Huang, Ruichen Jia, Kemin Wang
Abstract
was obtained with high selectivity. With the advantages of being simple, cost-effective and ultrasensitive, the biosensor offers potential for the early clinical diagnosis of tumors.
Topics & Concepts
AptamerMicrovesiclesDNAExosomeMolecular biologyComputational biologyNanotechnologyChemistryBiologymicroRNABiochemistryMaterials scienceGeneExtracellular vesicles in diseaseAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery