Optimizing Vaccine Trials for Enteric Diseases: The Enterics for Global Health (EFGH) <i>Shigella</i> Surveillance Study
Kirsten Vannice, Calman A. MacLennan, Jessica E. Long, A. Duncan Steele
Abstract
Abstract In this introductory article, we describe the rationale for the Enterics for Global Health (EFGH) Shigella surveillance study, which is largely to optimize the design and implementation of pivotal Shigella vaccine trials in the target population of infants and young children living in low- and middle-income countries. Such optimization will ideally lead to a shorter time to vaccine availability in the target population. We also provide a brief description of the articles included in the supplement.
Topics & Concepts
MedicineShigellaEnteric virusEnteric feverShigellosisTraveler's diarrheaPathogenic organismVirologyImmunologySalmonellaTyphoid feverDiarrheaMicrobiologyInternal medicineBiologyGeneticsBacteriaViral gastroenteritis research and epidemiologyEscherichia coli research studiesChild Nutrition and Water Access