Mannose-methyl-β-cyclodextrin suppresses tumor growth by targeting both colon cancer cells and tumor-associated macrophages
Yoshitaka Ohno, Maiko Toshino, Ahmed Fouad Abdelwahab Mohammed, Yukio Fujiwara, Yoshihiro Komohara, Risako Onodera, Taishi Higashi, Keiichi Motoyama
Topics & Concepts
ApoptosisIn vivoAutophagyCancer researchChemistryMannose receptorPI3K/AKT/mTOR pathwayColorectal cancerMannoseIn vitroCancer cellCancerProtein kinase BMacrophageBiologyMedicineBiochemistryInternal medicineBiotechnologyNanoparticle-Based Drug DeliveryCancer, Lipids, and MetabolismImmune cells in cancer