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Spinal cord injury target-immunotherapy with TNF-α autoregulated and feedback-controlled human umbilical cord mesenchymal stem cell derived exosomes remodelled by CRISPR/Cas9 plasmid

Baocheng Wang, Minmin Chang, Renwen Zhang, Jin Wo, Bowen Wu, Hua Zhang, Zhigang Zhou, Zhizhong Li, Feng Zhang, Cheng Zhong, Shujie Tang, Shuxian Yang, Guodong Sun

2021Biomaterials Advances48 citationsDOI

Topics & Concepts

Mesenchymal stem cellMedicineMicrovesiclesProinflammatory cytokineSpinal cord injuryImmunologyInflammationCancer researchTumor necrosis factor alphaExosomeUmbilical cordStem-cell therapySpinal cordBiologyPathologymicroRNAGeneBiochemistryPsychiatryExtracellular vesicles in diseaseRNA Interference and Gene DeliverySpinal Cord Injury Research
Spinal cord injury target-immunotherapy with TNF-α autoregulated and feedback-controlled human umbilical cord mesenchymal stem cell derived exosomes remodelled by CRISPR/Cas9 plasmid | Litcius