Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine
Omar Mossad, Bérénice Batut, Bahtiyar Yılmaz, Nikolaos Dokalis, Charlotte Mezö, Elisa Nent, Lara Susann Nabavi, M. Mayer, Feres José Mocayar Marón, Joerg M. Buescher, Mercedes Gomez de Agüero, Antal Szalay, Tim Lämmermann, Andrew J. Macpherson, Stephanie C. Ganal‐Vonarburg, Rolf Backofen, Daniel Erny, Marco Prinz, Thomas Blank
Topics & Concepts
MicrogliaGut floraOxidative stressTranscriptomeGut–brain axisBiologyMitochondrionReactive oxygen speciesImmunologyInflammationCell biologyGene expressionEndocrinologyGeneBiochemistryNeuroinflammation and Neurodegeneration MechanismsGut microbiota and healthTryptophan and brain disorders