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The Alkyne Zipper Reaction: A Useful Tool in Synthetic Chemistry

Åshild Moi Sørskår, Helge Ø. K. Stenstrøm, Yngve Stenstrøm, Simen Antonsen

2022Reactions10 citationsDOIOpen Access PDF

Abstract

The alkyne zipper reaction is an internal-to-terminal alkyne isomerization reaction with many interesting applications in synthetic chemistry, as it constitutes an efficient means of achieving acetylene functionalization. A review of its applications in synthesis processes is presented in this paper, with a brief overview of the mechanistic features of the alkyne zipper reaction, as well as a brief overview of its future potential.

Topics & Concepts

ZipperAlkyneChemistryAcetyleneIsomerizationCombinatorial chemistryTerminal (telecommunication)NanotechnologyComputer scienceOrganic chemistryMaterials scienceCatalysisAlgorithmTelecommunicationsChemical Synthesis and AnalysisClick Chemistry and ApplicationsSynthetic Organic Chemistry Methods