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Empowering boronic acids as hydroxyl synthons for aryne induced three-component coupling reactions

Rong Fan, Shihan Liu, Qiang Yan, Yun Wei, Jingwen Wang, Yu Lan, Jiajing Tan

2023Chemical Science23 citationsDOIOpen Access PDF

Abstract

Boronic acids as a tunable hydroxy source display a unique reactivity paradigm through hitherto unknown aryne-induced multicomponent reactions.

Topics & Concepts

SynthonAryneComponent (thermodynamics)ChemistryCoupling (piping)Boronic acidCoupling reactionCombinatorial chemistryOrganic chemistryMaterials scienceCatalysisPhysicsThermodynamicsMetallurgyCyclization and Aryne ChemistryChemical synthesis and alkaloidsCatalytic Alkyne Reactions
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