Saikosaponin B2 ameliorates depression-induced microglia activation by inhibiting ferroptosis-mediated neuroinflammation and ER stress
Xinmei Wang, Shanshan Li, Jiayu Yu, Wenlin Wang, Zhuoqi Du, S. Paul Gao, Yin Ma, Ruixin Tang, Ting Liu, Shiping Ma, Qiang Fu, X Deng
Topics & Concepts
NeuroinflammationMicrogliaPharmacologyLipopolysaccharideTail suspension testBehavioural despair testChemistryEndoplasmic reticulumLipid peroxidationOxidative stressMedicineBiologyInflammationImmunologyBiochemistryEndocrinologyHippocampusAntidepressantFerroptosis and cancer prognosisTryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms