Formulation and optimization of lornoxicam-loaded bilosomes using 23 full factorial design for the management of osteoarthritis in rats: Modulation of MAPK/Erk1 signaling pathway

Abeer Salama, Hadeer A. El-Hashemy, Asmaa Badawy Darwish

2022Journal of Drug Delivery Science and Technology40 citationsDOI

Topics & Concepts

LornoxicamOsteoarthritisIn vivoMAPK/ERK pathwayFactorial experimentZeta potentialDiclofenac SodiumChemistryPharmacologyDrug deliveryBiomedical engineeringKinaseMaterials scienceBiochemistryMedicineChromatographyNanotechnologyBiologyMathematicsAnalgesicPathologyNanoparticleBiotechnologyAlternative medicineStatisticsInflammatory mediators and NSAID effectsAntimicrobial Peptides and ActivitiesNatural product bioactivities and synthesis