Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop
Francesco Marangoni, Ademi Zhakyp, Michela Corsini, Shannon N Geels, Esteban Carrizosa, Martin Thelen, V. Mani, Jasper N. Prüßmann, Ross D. Warner, Aleksandra J. Ozga, Mauro Di Pilato, Shivashankar Othy, Thorsten R. Mempel
Topics & Concepts
BiologyCTLA-4FOXP3CD28Tumor microenvironmentImmunologyCell biologyT cellPopulationImmune systemDownregulation and upregulationCancer researchGeneticsMedicineGeneEnvironmental healthT-cell and B-cell ImmunologyImmunotherapy and Immune ResponsesImmune Cell Function and Interaction